My Experience Working While Diagnosed With Myasthenia Gravis

3 Cases of MG Possibly Caused by COVID-19 Vaccination: Report

Researchers in Italy have reported three cases of myasthenia gravis (MG) they say may possibly have been caused by a vaccine against SARS-CoV-2, the virus that causes COVID-19. “Clinicians should be aware of possible new-onset MG after SARS-CoV-2 vaccination, especially with the current recommendation of booster doses,” the team…

This Is What Good Care Should Feel Like

On Aug. 8, I had an appointment with a new neurologist. I was apprehensive about it because he would be the second neurologist I’d see at Veterans Affairs (VA) since our move to Wisconsin. I was quite happy with the neurologist I’d met when we got here, when I…

European Commission OKs Vyvgart for AChR-positive Generalized MG

The European Commission has approved Vyvgart (efgartigimod) as an add-on to standard treatment for adults with generalized myasthenia gravis (gMG) who are positive for antibodies against acetylcholine receptor (AChR), the most common type of MG-driving antibody. “We share the excitement with the European gMG community in bringing a…

Sanofi Pauses Recruitment in All Phase 3 Trials of Tolebrutinib

Sanofi has decided to pause recruitment globally in its Phase 3 clinical trials of tolebrutinib, an experimental BTK inhibitor, based on recommendations from the independent data monitoring committee (iDMC) overseeing the trials. The company has several ongoing studies investigating tolebrutinib’s effectiveness and safety, including one testing the investigational therapy…

Cancer Immunotherapy Imfinzi Tied to Myasthenic Crisis

The cancer immunotherapy Imfinzi (durvalumab) may, in rare cases, trigger myasthenic crises — a serious complication of myasthenia gravis (MG) that can lead to respiratory failure. A recent case report described how an 82-year-old woman on MG remission experienced a myasthenic crisis following treatment with Imfinzi for advanced-stage lung cancer.

Adding IV Immunoglobin to Steroids Better Treats Children with OMG

A combination of glucocorticoids and intravenous immunoglobulin (IVIG) is more effective at normalizing immune responses and easing disease symptoms in children with ocular myasthenia gravis (OMG) than glucocorticoids alone, a study showed. The combination also could allow for a shorter duration and lower dose of glucocorticoids, also known…