Since its approval in the U.S. in 2023 for people with generalized myasthenia gravis (gMG), Rystiggo (rozanolixizumab-noli) has been prescribed to a wide range of adults with the autoimmune disease — but, according to researchers, with little understanding of the real-life “profile” of patients starting the infusion therapy.
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An early drop in immunoglobulin G (IgG), a type of antibody, may help predict how well patients with generalized myasthenia gravis (gMG) respond to a class of treatments called FcRn inhibitors, a study suggests. The analysis focused on patients with antibodies that mistakenly target acetylcholine receptors (AChRs). Researchers analyzed…
Sexual dysfunction is common among adults with myasthenia gravis (MG) and appears to be associated with impairment of the autonomic nervous system, which regulates involuntary bodily processes, a study shows. “These findings support an association between autonomic dysfunction and [sexual dysfunction] in patients with MG beyond psychosocial factors alone,”…
Two interconnected themes — community and hope — dominated the conversations at a recent gathering of people living with neuromuscular diseases. Lily Sander, MDA National Ambassador, speaking at MDA Engage: Dallas. (Photo by Tara Haelle) Lily Sander, national ambassador for the Muscular Dystrophy Association (MDA), hit on those…
Depression and fatigue significantly lower the quality of life for people with myasthenia gravis (MG), even when their muscle weakness appears medically stable and well controlled, a study has found. The findings highlight that checking physical strength alone is not enough to measure how well a patient is doing…
The financial burden of myasthenia gravis (MG) extends well beyond medication, hospital stays, and doctor visits, with reduced ability to work, lost income, and a poorer quality of life accounting for a substantial share of the disease’s overall impact on patients and society. That’s according to a systematic review…
With a wide range of treatments available for myasthenia gravis (MG), it’s important to individualize treatment to each person’s needs, depending on their symptoms and what their life was like before they developed the disease, according to a speaker at a recent MDA Engage event. “We’ve made…
Six weeks of treatment with Rystiggo (rozanolixizumab-noli) appears as effective as Vyvgart (efgartigimod alfa-fcab) at easing symptoms of generalized myasthenia gravis (gMG), reducing its impact on daily life, and improving quality of life, according to an indirect comparison analysis of treatment options. The analysis, based on data…
People with myasthenia gravis (MG) in a Canadian patient group reported better quality of life than those in a U.S. group, even though their experiences getting diagnosed were broadly similar, a study found. The differences remained statistically significant after researchers accounted for patients’ age, sex, and disease severity. These…
Note: This story was updated Oct. 21, 2026, to clarify that the autoinjector and syringe versions of Zilbrysq contain the same formulation of the therapy’s active ingredient. Beginning early next year, certain adults in the U.S. with generalized myasthenia gravis (gMG) will have a new option for receiving the…
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