News

FDA clears Phase 2 trial testing C5 inhibitor IM-101 in MG patients

The U.S. Food and Drug Administration (FDA) has cleared the launch of a Phase 2 clinical trial testing IM-101, ImmunAbs’ investigational therapy for myasthenia gravis (MG). The multicenter, placebo-controlled trial is expected to enroll up to 90 people with MG who will receive IM-101 or a placebo once monthly.

MG Awareness Month focuses on community, action

Organizations are holding events and activities in June in recognition of Myasthenia Gravis Awareness Month, an annual observance that aims to raise awareness of myasthenia gravis (MG), an autoimmune disease that affects 90,000-100,000 people in the U.S. alone. “Throughout June, Myasthenia Gravis News is recognizing awareness month with a…

Tear-based antibody tests may help diagnose ocular MG: Study

Using tears to test for self-reactive antibodies to help diagnose ocular myasthenia gravis (OMG) is more accurate than using blood samples, according to a study that found nearly all patients who tested negative for these antibodies in the blood had a positive result in tears. “Tear-based testing offers a…

Vyvgart may be safer, more effective than IVIG in older patients

Vyvgart (efgartigimod alfa-fcab) may be safer and more effective than intravenous immunoglobulin (IVIG) therapy in elderly people with generalized myasthenia gravis (gMG), a study shows. In elderly Chinese patients with gMG who were positive for antibodies targeting the acetylcholine receptor (AChR), Vyvgart eased symptoms after four and…

Enrollment opens in Phase 1 trial of NKX019 cell therapy in gMG

Enrollment is open in an investigator-initiated clinical trial to evaluate cell therapy NKX019 in people with myasthenia gravis (MG). Nkarta, the therapy’s developer, made the announcement in a company press release. Researchers at the University of California, Irvine, and the University of Kansas Medical Center are leading the…

Robotic thymectomy safe, effective for treating MG: Study

Robotic thymectomy is a safe and effective treatment for people with myasthenia gravis (MG), including patient groups that have historically showed poorer outcomes, a study found. Five years after undergoing robotic thymectomy, a minimally invasive surgery to remove the thymus gland, 84% of patients saw their MG…