News

Titin antibody, hospitalizations linked in non-thymoma MG

The presence of antibodies targeting titin, a type of muscle protein, in patients with myasthenia gravis (MG) not associated with a thymus tumor is related to more frequent hospitalizations, according to a study in China. Frequent hospitalizations hurt quality of life and mental health for people with MG, and…

Vyvgart a rapid, effective treatment for impending myasthenic crisis

Treatment with Vyvgart (efgartigimod) may rapidly and safely ease symptoms during an impending myasthenic crisis in people with myasthenia gravis (MG), according to a study in China. Impending myasthenic crisis, or IMC, refers to symptoms rapidly worsening within a short time that may lead to a myasthenic crisis,…

IVIG agent safe, may be effective as maintenance therapy for gMG

A maintenance regimen using an intravenous immunoglobulin (IVIG) therapy may reduce disease severity and improve function in people with generalized myasthenia gravis, according to data from a Phase 2 clinical trial. IVIG is commonly used to treat acute symptom worsening in people with myasthenia gravis (MG). The …

Long-term use of tacrolimus found safe, effective in MG in study

Long-term use of the immunosuppressant tacrolimus was found to be safe and effective in myasthenia gravis (MG) patients with self-reactive antibodies targeting muscle-specific kinase, or MuSK — a protein important in nerve-muscle communication — according to the findings of a new study by researchers in China. Treatment with tacrolimus significantly…

KYV-101 granted orphan drug status for MG in Europe

The European Medicines Agency granted orphan drug status to the experimental cell therapy KYV-101 to treat myasthenia gravis (MG). The designation is given to medicines that aim to treat life-threatening or chronic debilitating conditions affecting no more than five in every 10,000 people. It provides companies with several…

Soliris eases AChR+ refractory myasthenia gravis disease severity

Soliris (eculizumab) effectively eased disease severity and reduced the need for immunosuppressive therapies in people with treatment-resistant generalized myasthenia gravis with anti-AChR antibodies, a real-world study in Italy shows. The treatment also reduced the number of disease exacerbations that required rescue therapy, such as intravenous immunoglobulin (IVIG)…

Intensive treatment most needed early in MG course: Study

Many adults with myasthenia gravis (MG) need intensive treatment in the first year after diagnosis, with younger patients and women facing a higher risk of death as the disease progresses, a study found. The researchers said the results point to a need for better treatment options. The study, “…