Author Archives: Marisa Wexler MS

Swallowing Muscle Test May Help Diagnose MG

The flexible endoscopic evaluation of swallowing-tensilon test (FTT), a new diagnostic tool for myasthenia gravis (MG), can be used to distinguish people with swallowing difficulties due to MG from those having similar symptoms caused by other conditions, according to a new study. The study, “Detecting myasthenia…

CAR T-cell Therapy Descartes-08 Eased MG Symptoms

Treatment with Descartes-08, an investigational CAR T-cell therapy, markedly eased symptoms of myasthenia gravis (MG) in three patients participating in a Phase 1/2 clinical trial assessing the therapy’s safety and preliminary efficacy. “This is the first clinical trial of CAR T-cells for an autoimmune disease. Naturally, the first patients…

Calprotectin, Inflammatory Protein, May Be Biomarker of MG Severity

An inflammation-associated protein called calprotectin is present at abnormally high levels in the blood of people with myasthenia gravis (MG), a new study reports. Data also suggest that levels of this protein might correlate with MG activity and severity, but further investigation is needed, according to its researchers. “There…

Immunovant Will Use $200M Investment to Advance IMVT-1401

Immunovant will use a $200 million strategic investment from Roivant Sciences to advance IMVT-1401, its investigational therapy for myasthenia gravis (MG) and other autoimmune conditions. A pivotal clinical trial testing IMVT-1401 in people with MG is expected to be launched within the next 12 months, according to…

Rare Case of MG Crisis Attributed to COVID-19 Vaccine

A very rare case of a myasthenia gravis (MG) crisis caused by the Moderna COVID-19 vaccine was described recently by researchers at St. Joseph’s Regional Medical Center in Paterson, New Jersey. “Although numerous studies have observed the relationship between active COVID infections and MG exacerbations, no known studies or…

Immunovant Planning Pivotal Trial of IMVT-1401

Following a review of available clinical data, Immunovant has announced plans to resume clinical testing of the investigational medication IMVT-1401 in myasthenia gravis (MG) and other autoimmune conditions. Following discussions with regulatory agencies, the company is planning to launch a potentially pivotal trial of IMVT-1401 in…

Early Swallowing Difficulty Tied to Worse Outcomes

People with myasthenia gravis (MG) who have difficulty swallowing are more likely to have poor clinical outcomes, according to a recent study. Data from the study also indicates that low levels of albumin — a protein found in the blood that helps transporting hormones and other key molecules in…

2021 Myasthenia Gravis Survey Results

BioNews Survey Infographic

Myasthenia Gravis News conducted a survey from Feb. 11-March 28 to gain greater insight into the characteristics of the MG community and disease management. Results of the survey have now been published. Click on the image to view the infographic, and click here to read the story.