As my twin with MG and I get older, our diets are an issue

gMG patients can carry treatment resistant autoantibodies, study finds

People with generalized myasthenia gravis (gMG) can carry certain types of self-reactive antibodies — proteins that mistakenly target the body’s own cells and tissues — that drive the disease but are treatment resistant, according to a new study by Yale School of Medicine researchers. These self-reactive antibodies, or autoantibodies,…

Gefurulimab found to ease gMG symptoms in global Phase 3 trial

Treatment with gefurulimab, an experimental self-administered injection therapy, outperformed a placebo in easing symptoms of generalized myasthenia gravis (gMG) among people with the chronic autoimmune disease, the results of a Phase 3 clinical trial show. The trial met both its primary and secondary endpoints, or goals, with treatment…

A fear of being paralyzed makes me push myself too hard

Note: This column was updated July 31, 2025, to clarify that the author fears temporary paralysis caused by severe muscle weakness, as opposed to a permanent paralysis. Yesterday, my brain and body collapsed because I was too tired and exhausted — not due to a myasthenia gravis (MG) flare-up…

Blinatumomab helps 2 women with resistant MG: Case report

A case report from Germany showed that two women with severe, treatment-resistant myasthenia gravis (MG) responded well to blinatumomab, suggesting the anti-cancer medication may offer a new option for hard-to-treat autoimmune diseases. “Since this first-in-human experience comprises two cases, our findings should be viewed as proof-of-concept rather than evidence…

Thymectomy surgery may cause long-term immune changes in MG

Surgery to remove the thymus gland led to a long-term reduction in levels of immune T-cells and to temporary changes in levels of proteins involved in regulating immune and inflammatory responses in people with myasthenia gravis (MG), a study shows. There were no significant effects on the levels of…