People with refractory myasthenia gravis (MG) who fail to respond to several treatments may be effectively treated with Vyvgart (efgartigimod alfa-fcab), regardless of the type of self-reactive antibodies they carry. That’s according to a systematic review and meta-analysis, which showed that patients treated with Vyvgart saw their symptoms…
Soliris (eculizumab) and Ultomiris (ravulizumab-cwvz) are generally safe and effective for easing symptoms of generalized myasthenia gravis (gMG) when used in everyday clinical practice. That’s according to data from the MG SPOTLIGHT Registry (NCT04202341), which was established to assess the long-term effectiveness of both therapies in…
Many companions accompany us on life’s journey, but perhaps the most constant of these is uncertainty. None of us knows what curveballs may come our way from one day to the next. Most people can relegate thoughts of curveballs to a dim recess in their minds, but those of us…
Treatment with the experimental injection therapy claseprubart (DNTH103) was well tolerated and appeared to ease symptoms of generalized myasthenia gravis (gMG) in a Phase 2 clinical trial involving people with the autoimmune neuromuscular condition. That’s according to top-line data announced by the therapy’s developer Dianthus Therapeutics. The…
Living with myasthenia gravis (MG) means I’ve spent more time in hospitals and clinics than I ever imagined I would. Most of the healthcare providers I’ve met have been kind, compassionate, and respectful. They’ve held my hand through scary procedures, explained complicated medical jargon in ways I could understand,…
On April 14, 1912, shortly before midnight, the Titanic struck an iceberg that would sink the ship and bring more than 1,500 people down to watery graves. Decades later, on Dec. 28, 1978, United Airlines Flight 173 circled in the sky south of Portland International Airport…
The first recommendation anyone gives you when you’re diagnosed with a chronic illness is always the same: rest. And for the past five years, I fully believed it. I told myself, and everyone else, that rest was the key to managing myasthenia gravis (MG). I built a life around…
An analysis of the Swedish MG registry suggests that adults with myasthenia gravis (MG) have an impaired quality of life, even when they show low disease activity. Muscle weakness affecting the limbs and breathing primarily drove a diminished quality of life. These findings indicate “an unmet medical need that…
A new Phase 3 clinical trial testing Kyverna Therapeutics’ cell therapy candidate KYV-101 in people with myasthenia gravis (MG) — a study the developer says “supports [a] clear and rapid path to [regulatory approval]” — is expected to start enrolling participants before the end of the year, according to…
I don’t enjoy going outside now as much as I did in my youth. I’m a homebody and I like it. This transition made me think of my twin, Aaron, who has myasthenia gravis (MG). Before MG, Aaron was a manual laborer who was very sociable and…
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