Povetacicept reduces disease activity in MG mouse model

Povetacicept reduces disease activity in MG mouse model

Povetacicept, a treatment for autoimmune diseases in the pipeline of Vertex Pharmaceuticals, reduced disease activity in a study with a mouse model of myasthenia gravis (MG) by lowering the levels of disease-causing antibodies in the bloodstream. Researchers also observed that povetacicept outperformed efgartigimod — approved as Vyvgart…

As my dumbbells collect dust, my twin loves to work out

You must love yourself to keep a healthy lifestyle. But I don’t exercise enough; in fact, I have 20-pound dumbbells collecting dust in a corner of my small condo here in Manila, the Philippines. I decided to ask my twin, Aaron, about his exercise routine, partly for inspiration. Aaron was…

Vyvgart found effective for 3 triple-seronegative gMG patients

Treatment with Vyvgart (efgartigimod) eased hard-to-treat symptoms for a trio of women with generalized myasthenia gravis (gMG) who tested negative for three antibodies commonly seen in the disease, according to a case series from China. Per the researchers, “this report describes three patients with triple-[seronegative] gMG successfully treated with efgartigimod,”…

A day in the water is just what the doctor ordered

Healing doesn’t always look like rest and stillness. Sometimes it looks like kicking your legs with wild abandon in a murky lake while your husband looks on amused, wondering how his 41-year-old wife suddenly turned into a giddy 10-year-old. I’ve always loved the water, and it’s where I’ve felt the…

How I keep moving forward in life with myasthenia gravis

Athena Sanchez graduates from Northern Arizona University. (Courtesy of Athena Sanchez) This is Athena Sanchez’s story: Living with myasthenia gravis (MG) is like constantly fighting a battle, and my body doesn’t always show up. I was diagnosed when I was just 18, barely out of high…