• This topic has 10 replies, 9 voices, and was last updated 1 month ago by Mike.
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    • #19315
      Jodi Enders

      Magnesium sulfate can be potentially dangerous for those with Myasthenia gravis. Drugs.com puts MG in the category of one of eight diseases that an individual could have in which they should avoid magnesium. It has the potential to worsen symptoms and lead to a crisis. 


      I have had both a primary care specialist and a Gastroenterologist recommend magnesium, aware I had MG but unaware of their potential dangerous interaction. 


      Have you for any reason used magnesium and experienced an adverse reaction? What have your health professionals mentioned to you about taking it?

    • #19442
      Charles Karcher

      Part of the cleansing process prior to a colonoscopy includes a magnesium solution.  After first giving the go ahead my neurologist changed his mind and recommended against using the magnesium solution.  My gastroenterologist had no problem deleting it from the prep so I question the need for it in the first place,  The procedure went through without the magnesium solution and without issues.

    • #19451

      Avoid magnesium. As a doctor I can tell you there is only a paragraph in textbooks about MG. Most non- neurologists don’t know all the meds that can worsen MG. You can print off a list and carry it around with you. When I am hospitalized and my magnesium gets low I speak to the doctor to find out my magnesium level. My neurologist says it is best to keep the level on the low side of normal

    • #19452
      Prosper Abusah

      I have MG for more than 25 years . I have severe muscle spasms of my hands and fingers and muscle cramps . I have been taking small doses of magnesium for years without much improvement in the spasms . Since last year I have been taking mega doses of magnesium and the muscle spasms have stopped . I have not noticed any deterioration in my MG symptoms . The list of medications and things mentioned to avoid when you have MG is endless .

    • #19453

      Hi Jodi, When I first consulted my neurologist in 2020, she told me that magnesium works against the action of AChR at the neuro-muscular junction, and that I must spot taking magnesium supplements

    • #19462
      Michael Chiesa

      My neurologist suggested taking it but I stopped after a year. Saw the warnings and didn’t notice any difference one way or the other. Need to go by what you are feeling, no one size fits all as we know. I was given Cipro and it is a Black Box Warming. Both Neurologist and Primary said don’t worry. Developed breathing issues so I tend to err on the side of caution with all drugs. Need to be your own advocate.


    • #19494

      I take a magnesium supplement every night and have not had a problem.  Most of the drugs on the list of drugs that may cause problems, do cause problems for me, but not all of them.

    • #19515
      Maureen Gosz

      What do you look up to find out what drugs or supplements are bad for MG?

    • #19518
      Marguerite Thibeau

      Magnesium is very necessary for healthy muscles, and easy to get through our diet without problems. Certain populations are low in magnesium as the soil in the area is low and not enough was available in food. Scotland had this problem.

      “Magnesium is in charge of numerous important functions in our body. In the power plants of our cells, the mitochondria, it is involved in generating the indispensable energy needed for all of the body’s processes. Magnesium activates about 600 enzymes in our body. It makes sure that hormones like insulin are stored and released. It is involved in the production of nerve messengers like serotonin, and protects our cardiac muscle from stress. In the skeleton, it is an essential factor in bone health. Finally, in our muscles, magnesium is responsible for their usual function together with calcium.”

      “A well-adjusted magnesium and calcium balance is indispensable for healthy muscle function. Whereas calcium is responsible for muscle tension, magnesium is in charge of muscle relaxation. It controls the transmission of impulses from nerves to muscles, ensures that the continued inflow of calcium is prevented and that the nerve excitability is lowered once again – which leads to the desired relaxation. For healthy adults, the German Nutrition Society recommends a daily magnesium intake of 300-400 mg depending on age and gender. If there is magnesium deficiency, there is excessive calcium in the muscle and it can no longer fully relax. This causes painful cramps.”

      High dose IV Magnesium is a problem for MG patients, and most be assessed by need by doctors aware of the issue for MG patients.  But most of us can look up foods rich in it, or use an appropriate supplement overseen by our doctors.


    • #19525

      Today I’m in the middle of my first 5-day IVIG infusion series and I hadn’t really eaten much of anything for about 2 weeks because of my swallowing difficulties. Upon admission they did bloodwork and my Magnesium was 1.6 so the admitting doc ordered Magnesium, of course. I am so fortunate that a couple of months ago I just happened to have read a comment by someone on this website that mentioned about not taking Mg for anything (like, for example, leg cramps). I looked around here and at other MG forum sites, did some more formal research and figured there was something about this so I did something I’ve never done in my life and refused the order. While an inpatient I dug around some more and, voila, Mg inhibits ACh production! I had to educate my nurses and the ordering MD and they soon realized what might have otherwise happened (exacerbate my flare-up or cause an MG crisis). My advice is to learn as much as you can about MG and known triggers because about 99% of the medical community know very little about MG, and there may be times that you’ll have to stand up and be strong and insistent and have some reference(s) handy to back up your decision. This website might have saved my life.

    • #19526

      I just wanted to be clear about my previous comment… I’m referring to not taking Mg ONLY during a flare-up. not while in remission.

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