The first participant has been dosed in a Phase 1/2a trial evaluating NMD670, NMD Pharma‘s investigational therapy for myasthenia gravis (MG). “I am pleased to announce that our lead program has entered the clinic. NMD670 has already shown great promise in preclinical studies and…
Treatment with Argenx‘s investigational therapy efgartigimod leads to significant and early reductions in the severity of generalized myasthenia gravis (gMG), regardless of the presence of antibodies against acetylcholine receptor (AChR), according to results from a Phase 3 clinical trial. Trial findings were presented earlier this month at…
Same But Different, a nonprofit U.K. group that uses art for social change, is inviting people to choose their favorite photographs in a calendar contest to heighten awareness of rare diseases, including amyotrophic lateral sclerosis (ALS). The organization’s panel of judges has pared the number of contest submissions to…
Tasks involving memory can be difficult for people with myasthenia gravis (MG) due to depression and the use of glucocorticosteroids, a study from Brazil found. The study, “Cognitive performance in patients with Myasthenia Gravis: an association with glucocorticosteroid use and depression,” was published in the…
A Phase 2 clinical trial of Harbour BioMed‘s investigational therapy batoclimab, also known as HBM9161, for myasthenia gravis (MG), has started dosing patients, the company said in a press release. The trial (NCT04346888) — being conducted at the Huashan Hospital in Shanghai, China — is…
For the first time, a real-world study comparing the effects of long-term intravenous (IVIG) and subcutaneous immunoglobulin (SCIG) maintenance therapy in adults with generalized myasthenia gravis (gMG) showed reduced impairments, less use of other medications, and improved…
A large-scale analysis of people with myasthenia gravis (MG) in North America revealed a higher prevalence of MG and other autoimmune disorders among their families, suggesting there may be a genetic component to the neuromuscular condition, a study reported. The…
Among people with myasthenia gravis (MG) and thymoma — a tumor of the thymus — being male and having more severe disease, advanced thymoma, or post-surgery complications predict poorer outcomes, a study from China suggests. In turn, anticholinesterase therapies taken early and before surgery to remove the thymus…
Altered levels of immune proteins associated with the complement system may be implicated in generalized myasthenia gravis (MG), a new study suggests. The study, “Changes in serum complements and their regulators in generalised myasthenia gravis,” was published in the European Journal of Neurology. The complement system…
Women with myasthenia gravis (MG) have a diminished quality of life compared with male patients, and are particularly affected by the number of additional diseases (comorbidities) they experience, a new study from China reports. They also have a less active lifestyle, which may reveal…
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