Author Archives: Aisha I Abdullah PhD

The rare case of a female patient who developed myasthenia gravis (MG) in association with Hodgkin’s lymphoma, a type of blood cancer, highlighted the link between these conditions and the therapeutic challenge they pose. Her case was described…

Three patients with myasthenia gravis (MG) were safely treated for COVID-19 with a combination of the antiviral medication Veklury (remdesivir) and the anti-inflammatory dexamethasone, while having no apparent worsening of their MG symptoms. Veklury…

Thymectomy, or surgical removal of the thymus, can lower medication use and lessen disease severity in people with myasthenia gravis (MG), regardless of age, sex, or medical history, an observational study has found. Data from the study also indicated that younger female patients with early onset MG, an…

In two of three myasthenia gravis (MG) patients who contracted COVID-19, the use of immunosuppressants did not cause an exacerbation or myasthenic crisis, a case study reports, suggesting the treatments may be safe and beneficial for this group of patients. “Despite these…

Rapid tapering of high-dose prednisone appears to be a feasible, safe, and effective option for people with moderate-to-severe generalized myasthenia gravis on a combination of corticosteroids and immunosuppressants, according to data from a Phase 4 trial. These findings were reported…

An international Phase 3 clinical trial assessing the efficacy, safety, and tolerability of rozanolixizumab as a treatment for generalized myasthenia gravis (MG) is currently recruiting participants at 114 study locations. Conducted by UCB BioSciences, the…

A specific haplotype — or genetic signature inherited from one parent — was identified as a risk factor for the development of generalized late-onset myasthenia gravis (LOMG) in the Italian population. A second haplotype was newly identified as having a potential…

Patients with myasthenia gravis (MG) who have one copy of an FCGRT gene variant have lower levels of circulating antibodies called immunoglobulin G (IgG) and are more likely to be resistant to intravenous immunoglobulin (IVIg) treatment, a small study found. The…

Early reduction of steroid and immunosuppressant therapy during Soliris (eculizumab) treatment to alleviate myasthenia gravis (MG) symptoms may result in disease aggravation and pure red cell aplasia (PRCA), according to a Japanese case study. PRCA is a form…

People with myasthenia gravis (MG) have a significantly higher risk of body-wide complications within three months of total hip or knee replacement surgery than patients without the rare disease, a study found. The analysis, “Increased rate…