Forest Ray PhD,  —

Forest Ray received his PhD in systems biology from Columbia University, where he developed tools to match drug side effects to other diseases. He has since worked as a journalist and science writer, covering topics from rare diseases to the intersection between environmental science and social justice. He currently lives in Long Beach, California.

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Therapeutic Plasma Exchange Eased Refractory MG

Therapeutic plasma exchange improved symptoms related to hard-to-treat myasthenia gravis, resulted in reduced use of immunosuppressants, and was well-tolerated by patients, according to a new study. That study, “Clinical experience with maintenance therapeutic plasma exchange in refractory generalized myasthenia gravis,” was published in the Journal of…

Ultomiris Helps Ease gMG Symptoms in Ongoing Phase 3 Trial

Ultomiris (ravulizumab-cwvz) rapidly and sustainably eased symptom severity in adults with generalized myasthenia gravis (gMG), according to top-line data from a Phase 3 trial. Alexion Pharmaceuticals, the therapy’s developer, now plans to submit regulatory applications requesting approval of Ultomiris for gMG in the U.S., Europe, and Japan, later…

Patient Dosing Begins in Phase 1/2a Trial of Oral NMD670

Patient dosing has begun in a Phase 1/2a clinical trial of NMD670, an investigational oral therapy by NMD Pharma aiming to improve motor abilities and quality of life for people with myasthenia gravis (MG). “We are pleased to announce the dosing of the first myasthenia gravis patient today…

Too Much Pyridostigmine May Increase Overactive Bladder Issues

High pyridostigmine doses cause overactive bladder issues in people with myasthenia gravis (MG), according to a recent study. Because of this, doctors should take patients’ bladder-related discomfort into account when deciding treatment regimens, and consider prescribing lower pyridostigmine doses or alternative therapies. The study, “Overactive…

MG May Mimic Stroke Symptoms, Case Report Suggests

Myasthenia gravis (MG) can mimic the symptoms of a stroke and should not be ruled out even in younger patients, a recent medical case report suggests. The report, “Myasthenia gravis masquerading as acute stroke: a case report,” was published in the PanAfrican Medical Journal. MG…

Double-Seropositive MG May Be Subtype of MuSK-MG, Study Suggests

A lesser known variety of myasthenia gravis (MG), called double-seropositive, appears to be a subtype of MuSK-antibody positive MG, a single-site study in China reports. Recognizing this subtype could help in properly diagnosing patients, allowing for better treatment outcomes, its scientists said. Their study, “AChRAb and…