A new under-the-skin injectable formulation of Vyvgart (efgartigimod alfa) has been approved by the European Commission for adults with generalized myasthenia gravis (gMG) who are positive for antibodies targeting the acetylcholine receptor (AChR) — the most common type of MG-causing antibody. This subcutaneous (under-the-skin) formulation now can be…
News
Spanish-speaking patients living with myasthenia gravis (MG) — and their caregivers, family members, friends, and anyone else seeking to learn more about the rare neuromuscular disease — are invited to join in the next meeting of the Virtual International Spanish MG Support Group, or Miastenia Gravis Grupo de Apoyo,…
The U.S. Food and Drug Administration (FDA) has cleared an investigational new drug (IND) application from Kyverna Therapeutics, giving the company the go-ahead to launch a Phase 2 clinical trial that will test its cell therapy, KYV-101, in people with myasthenia gravis (MG). This is the fifth IND…
The experimental treatment povetacicept (ALPN-303) may be more effective than current available treatments for myasthenia gravis (MG), according to preclinical data from Alpine Immune Sciences, which is developing the therapy. Specifically, povetacicept outperformed Vyvgart (efgartigimod) and off-label rituximab at reducing disease activity in a mouse model of the…
The U.S. Food and Drug Administration (FDA) has given Cabaletta Bio the go-ahead to launch a Phase 1/2 clinical trial testing its cell therapy CABA-201 in people with generalized myasthenia gravis (gMG). The upcoming trial is expected to enroll a dozen adults with gMG — six who are positive…
Both propofol and sevoflurane — two types of agents for anesthesia management — were found to be safe and effective when used without muscle relaxants in myasthenia gravis (MG) patients undergoing surgery to remove the thymus gland. These findings, involving patients at a hospital in Vietnam, highlight what researchers…
Negative emotions, a personality trait known as neuroticism, are more likely in people with myasthenia gravis (MG) than those without this disease, and may explain why these patients appear to be more liable to depression and anxiety, a study suggests. MG patients also scored lower than healthy adults for openness…
Women with myasthenia gravis (MG) have more severe disease and worse quality of life than men, according to a study in Germany, which also found overweight patients had poorer quality of life too. The delay in being diagnosed was also longer for women than for men, which may result…
People living with generalized myasthenia gravis (gMG) in the U.S. who experience certain barriers to healthcare reported major economic concerns in a new patient survey. These patients highlighted issues related to managing funds for emergency care, loss of income, and other non-medical expenses as contributing to a greater economic…
The U.S. Food and Drug Administration (FDA) has approved zilucoplan, a once-daily injection therapy to now be marketed under the brand name Zilbrysq, for adults with generalized myasthenia gravis (gMG) who are positive for antibodies targeting the acetylcholine receptor (AChR). With this approval, Zilbrysq has now become the…
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