Long-term immunotherapy may cause anemia in female patients with myasthenia gravis (MG), according to a Japanese study that found that women with this blood condition — one of the potential side effects of immunotherapy — had significantly worse disease severity. Anemia, a condition marked by a low…
Pyridostigmine is perceived as being moderately effective at easing myasthenia gravis (MG) symptoms, but often is accompanied by side effects, a study of Dutch patients revealed. Researchers noted the findings do not indicate a need for changes to current guidelines, which recommend the use of pyridostigmine as a first-line…
Virtis Health announced that it will open two ambulatory centers in Ohio — one in Columbus and the other in Cleveland — for people in need of infusion therapies, including those with myasthenia gravis (MG). Virtis is a division of Soleo Health, a pharmacy specialized in the…
Researchers in Iran reported the first case of myasthenia gravis (MG) following a Sinopharm vaccination against SARS-CoV-2, the virus that causes COVID-19. The report follows evidence of a possible link between COVID-19 vaccination and MG. While the mechanisms remain unclear, “if muscle weakness, ocular and bulbar [neck and facial]…
Subcutaneous immunoglobulin therapy (SCIg) — given by under-the-skin injection — was well-tolerated and effective in the management of adults with myasthenia gravis (MG), a small study has found. Although the therapy is approved for other diseases related to immune system deficiency, and is currently under investigation as an…
Neurologists find both Vyvgart (efgartigimod) and Ultomiris (ravulizumab-cwvz) effective for treating generalized myasthenia gravis (gMG), but believe Ultomiris has a more convenient dosing schedule while Vyvgart may have a better safety profile. That’s according to a recent analysis by the market intelligence firm Spherix Global Insights.
The Japanese Ministry of Health, Labor and Welfare (MHLW) has approved Ultomiris (ravulizumab) for treating generalized myasthenia gravis (gMG). The approval covers adults positive for antibodies against the acetylcholine receptor (AChR) — the most common type of MG-driving autoantibody — and who either don’t respond adequately to…
Risk factors for converting ocular myasthenia gravis (MG) to generalized myasthenia gravis (gMG) after a thymectomy, or thymus removal surgery, were identified in a recent study. Specifically, abnormalities in a repetitive nerve stimulation (RNS) test and having a specific thymus tumor subtype called B2/B3 were predictive of gMG…
Levels of the tumor necrosis factor receptor-associated factor 6 (TRAF6) protein in immune B-cells are higher than normal in people with myasthenia gravis (MG), and may be a useful biomarker of inflammation in MG, a study suggested. The observed elevations were more pronounced among patients with generalized MG…
About one in 10 patients with thymic carcinoma — a rare type of malignant tumor in the thymus gland — also has myasthenia gravis (MG), but this does not appear to reduce their lifespan, according to a study of data from an international registry. The study, “Does myasthenia…
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