Taking MG to the mall: My tips to make shopping work

Vyvgart Hytrulo formulation available for generalized MG in US

The recently approved prefilled syringe formulation of Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) that offers the possibility of self-administration is now available in the U.S. for eligible adults with generalized myasthenia gravis (gMG) who have antibodies against acetylcholine receptors (AChRs). These ready-to-use syringes are intended to be…

Enrollment complete in Phase 2 trial testing DNTH103 for gMG

Enrollment is now complete for a Phase 2 clinical trial testing Dianthus Therapeutics‘ treatment candidate DNTH103 in people with generalized myasthenia gravis (gMG). According to the developer, the initial results from the global study, dubbed MAGIC (NCT06282159), are expected by early fall. MAGIC was launched early…

Coping with chronic illness: Who am I to judge?

Along with the certainty of death and taxes, life is mostly about mitigating stress and finding peace within the chaos. As we navigate life, uncertainty abounds, and some of us deal with more of it than others. I’m learning that young people say we huff “copium” when grappling with uncertainty,…

FDA approves J&J’s nipocalimab, now Imaavy, to treat gMG

The U.S. Food and Drug Administration (FDA) has approved nipocalimab as a treatment for adults and adolescents, ages 12 and older, with generalized myasthenia gravis (gMG) who have antibodies against the acetylcholine receptor (AChR) or muscle-specific kinase (MuSK) proteins. The newly approved therapy will be sold by developer…

Vyvgart outperforms standard treatment in real-world study

Vyvgart (efgartigimod alfa-fcab) is faster and more effective at reducing symptoms to a minimum than standard treatment with corticosteroids and/or immunosuppressants in adults with myasthenia gravis (MG), a real-world study showed. Data showed that Vyvgart was particularly effective at easing symptoms affecting muscles involved in breathing, speech, and…

Anti-MuSK antibody levels don’t reflect MG disease severity: Study

Levels of antibodies against muscle-specific kinase (MuSK) are not reflective of disease severity in people with MuSK-positive myasthenia gravis (MG), according to a study. “Given our results, MuSK autoantibodies are not suitable as biomarkers for clinical severity or prognosis in MuSK-positive MG,” the researchers wrote. The study, “…

Learning to recognize the signs and symptoms of stress

I used to think stress always looked like a dramatic meltdown. You know, ugly crying, yelling into a pillow, eating a bag of cheese curls while binge-watching trashy TV. (Been there, no regrets.) But stress is sneakier than that. She doesn’t always knock loudly. Sometimes she’ll tiptoe in wearing…