News

Zilucoplan, now Zilbrysq, approved by FDA for AChR-positive gMG

The U.S. Food and Drug Administration (FDA) has approved zilucoplan, a once-daily injection therapy to now be marketed under the brand name Zilbrysq, for adults with generalized myasthenia gravis (gMG) who are positive for antibodies targeting the acetylcholine receptor (AChR). With this approval, Zilbrysq has now become the…

Vyvgart now approved in Canada for adults with AChR-related gMG

Health Canada has approved Vyvgart (efgartigimod alfa-fcab) to treat adults with generalized myasthenia gravis (gMG) who are positive for antibodies targeting the acetylcholine receptor (AChR), the most common target of MG-causing antibodies. The approval is based on positive data from the Phase 3 ADAPT clinical trial (NCT03669588),…

Retroviral agents for HIV may have caused MG in woman: Case report

A 44-year-old woman positive for the human immunodeficiency virus (HIV) developed myasthenia gravis (MG) after receiving treatment with antiretroviral agents. While no clear guidelines exist for treating MG in HIV-infected patients, researchers noted  the woman was successfully treated with prednisone, azathioprine, and plasma exchange. According to them, this approach…