Determining whether two types of immune cells — T follicular helper cells and activated dendritic cells — are present or lacking in a thymoma, in addition to the levels of specific genes, may help to predict the risk of myasthenia gravis (MG) among people with these tumors, a small study suggests.
A type of myasthenia gravis (MG) caused by the presence of self-reactive antibodies targeting muscle-specific kinase (MuSK) affects mostly women and manifests with eye and bulbar symptoms (those involving the face and neck), according to a single-center study in Northwest China. In these cases, MG can be successfully managed…
People with myasthenia gravis (MG) have an increased risk of developing systemic lupus erythematosus or SLE, another type of autoimmune disorder, according to recent study findings that suggest “a real association between these two diseases.” Especially at risk are African American women, those who had surgery to remove…
An 82-year-old man was diagnosed with myasthenia gravis (MG) shortly after receiving his second dose of the BioNTech/Pfizer COVID-19 vaccine, a case study reports. He lacked typical MG symptoms, but instead developed speech problems (dysarthria) and swallowing difficulties (dysphagia). “Diagnosis of COVID-19 vaccine associated new onset myasthenia gravis…
“Human-on-a-chip” technology developed by Hesperos can be used to model myasthenia gravis (MG), a new study shows. “This system has the potential to help researchers understand which mechanisms are driving a specific patient’s disease, including presence of particular autoantibodies [self-targeting antibodies], and could be used to further evaluate…
Comorbidities — co-existing illnesses like hypertension — tend to be more common in older patients with myasthenia gravis (MG) and to increase with advancing age, a study of patient registry data reports. The presence of comorbidities, however, did not differ among these adults based on age at MG onset. The study…
In patients with myasthenia gravis (MG) with an associated thymus tumor, being male, having poorer lung function, more severe disease, receiving into-the-vein anesthetics, and spending a longer time in surgery are all associated with a higher risk of prolonged ventilation following thymus removal surgery. The study with that finding,…
Zai Lab is planning — in the first half of 2022 — to ask Chinese authorities to approve efgartigimod (ARGX-113) as a treatment for generalized myasthenia gravis (gMG) in that country. The therapy, being developed by Argenx and designed to lessen the body’s immune attacks against…
In people with ocular myasthenia gravis (OMG), disease onset during adulthood, the presence of nerve abnormalities, anti-acetylcholine receptor (AChR) autoantibodies, and a thymus tumor, all increase the risk of disease generalization to the rest of the body, a multicenter study in China has found. Notably, in contrast to…
Diabetes, which causes blood sugar levels to rise abnormally, may trigger a stronger immune response and worsen myasthenia gravis (MG) symptoms, a study in a rat disease model suggests. If its findings hold true in people, they could provide evidence of the importance of blood sugar control in easing…
Get regular updates to your inbox.
