The onset of myasthenia gravis (MG) occurs at a significantly younger age in people who smoke, a study has found. Women who smoked at MG onset, or within 10 years before its onset, were significantly younger at disease onset than men. Yet, no sex differences were seen among those…
News
Intravenous immunoglobulin therapy was not effective at reducing the daily dose of corticosteroids for treating myasthenia gravis (MG), a multicenter Phase 2 trial shows. “These results suggest that immunomodulation alone was insufficient to facilitate dose reduction,” the researchers wrote. The trial results were reported in the study, “…
Nearly six months of treatment with telitacicept (RC18), an anti-inflammatory developed by RemeGen, safely lessened disease severity in adults with myasthenia gravis (MG) positive for acetylcholine receptor (AChR) antibodies. That’s according to new data from an ongoing Phase 2 trial in China. “The latest Phase II clinical study…
Treatment with the diabetes medication metformin suppresses the growth of immune T- and B-cell subsets that are implicated in the development of myasthenia gravis (MG), according to a study in a rat model of the neuromuscular disease. Metformin appeared to exert these positive effects by reversing the abnormal levels…
Cour Pharmaceuticals is launching a Phase 1b/2a proof-of-concept study to evaluate the safety and preliminary effectiveness of its investigational therapy CNP-106, an immune-modifying nanoparticle that’s designed to reprogram the immune system in adults with myasthenia gravis (MG). The announcement follows the U.S. Food and Drug Administration’s (FDA) approval of…
The high blood sugar levels that characterize diabetes may prompt immune cells to be activated that can drive and worsen myasthenia gravis (MG), a recent study suggests. These findings indicate that tightly controlling blood sugar levels may benefit MG patients who also have diabetes. The study, “Diabetes mellitus aggravates…
Virtis Health has opened two ambulatory centers in Alabama for people with myasthenia gravis (MG) and other disorders that call for infusion therapies. The new Alabama centers in Mobile and Birmingham are available to patients statewide, in addition to residents of those cities. Their openings follow that of…
Telitacicept (RC18), an anti-inflammatory therapy developed by RemeGen, has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA) as a potential treatment for myasthenia gravis (MG). Orphan drug designation, or ODD, is given to therapies that have the potential to treat rare diseases, defined…
NMD670 safely improved muscle function and strength in a small clinical trial of people with myasthenia gravis (MG), the therapy’s developer, NMD Pharma, announced. “These trial results represent an important milestone for NMD Pharma as they provide the first clinical proof of mechanism for our novel ClC-1 inhibitor…
A new ambulatory center, operated by Virtis Health, has opened its doors in the Atlanta, Georgia, area for myasthenia gravis patients (MG) and others who require infusion treatments. Virtis is a division of Soleo Health, a pharmacy that specializes in the provision of infusion therapies to homes…
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