News

Smoking Linked to Earlier Onset of MG

The onset of myasthenia gravis (MG) occurs at a significantly younger age in people who smoke, a study has found. Women who smoked at MG onset, or within 10 years before its onset, were significantly younger at disease onset than men. Yet, no sex differences were seen among those…

IVIG Not Effective at Lowering Corticosteroid Dose in MG Patients

Intravenous immunoglobulin therapy was not effective at reducing the daily dose of corticosteroids for treating myasthenia gravis (MG), a multicenter Phase 2 trial shows. “These results suggest that immunomodulation alone was insufficient to facilitate dose reduction,” the researchers wrote. The trial results were reported in the study, “…

FDA Clears Proof-of-concept Study for CNP-106 Immune Therapy

Cour Pharmaceuticals is launching a Phase 1b/2a proof-of-concept study to evaluate the safety and preliminary effectiveness of its investigational therapy CNP-106, an immune-modifying nanoparticle that’s designed to reprogram the immune system in adults with myasthenia gravis (MG). The announcement follows the U.S. Food and Drug Administration’s (FDA) approval of…

Telitacicept Wins Orphan Drug Status to Treat Myasthenia Gravis

Telitacicept (RC18), an anti-inflammatory therapy developed by RemeGen, has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA) as a potential treatment for myasthenia gravis (MG). Orphan drug designation, or ODD, is given to therapies that have the potential to treat rare diseases, defined…

NMD670 Shows Signs of Efficacy in Small Phase 1/2a Trial

NMD670 safely improved muscle function and strength in a small clinical trial of people with myasthenia gravis (MG), the therapy’s developer, NMD Pharma, announced. “These trial results represent an important milestone for NMD Pharma as they provide the first clinical proof of mechanism for our novel ClC-1 inhibitor…