The approved therapy Zilbrysq (zilucoplan) safely and effectively eases symptoms and improves function and quality of life for people with generalized myasthenia gravis (gMG) who are positive for antibodies against the acetylcholine receptor (AChR) protein. These are the main findings of a real-world study from Italy, which also showed…

Adding a single infusion of Vyvgart (efgartigimod alfa-fcab) to treatment typically given before a thymectomy, or the surgical removal of the thymus gland, results in greater clinical and laboratory improvements in people with myasthenia gravis (MG). That’s according to a small, single-center study in China, which showed that…

A study of myasthenia gravis (MG) patients lends support to “ongoing efforts to develop efficacious MG-specific treatments with minimal short- and long-term adverse effects,” researchers said. The U.S.-based study found that MG patients aged 65 and older have higher rates of death than those without the disease, mainly due to…

The U.S. Food and Drug Administration (FDA) has approved inebilizumab as a treatment for generalized myasthenia gravis (gMG). The newly approved therapy, which developer Amgen will market under the brand name Uplizna, is specifically indicated for adults with gMG who are positive for antibodies targeting the acetylcholine…

For people with generalized myasthenia gravis (MG) in the U.S., getting a correct diagnosis is often a difficult and stressful process that can take more than two years from the time of symptom onset, a study showed. Findings suggest that people with MG often feel dismissed by doctors when…

The Myasthenia Gravis Foundation of America (MGFA) has published a new resource designed to help people with myasthenia gravis (MG) understand the medical jargon and terminology that’s commonly used to discuss the disease. The MG Lexicon offers succinct definitions for a wide range of terms. The definitions…

Blood levels of five proteins involved in the body’s inflammatory response may be used to diagnose myasthenia gravis (MG) and distinguish it from other autoimmune diseases, according to new research findings from scientists working in Sweden and Germany. The research team also identified other small sets of inflammatory proteins…

Imaavy (nipocalimab) has been approved in the European Union as an add-on to standard of care treatment for adults and adolescents, ages 12 and older, with generalized myasthenia gravis (gMG) and self-reactive antibodies targeting the acetylcholine receptor (AChR) or muscle-specific kinase (MuSK). The decision by the European Commission makes…

An enzyme, called S-1117, can disarm self-reactive immunoglobulin G (IgG) antibodies targeting the acetylcholine receptor (AChR) that drive most cases of myasthenia gravis (MG), according to a study that used blood samples from patients. “This study presents S-1117, an IgG-specific protease [a protein-degrading enzyme], as a promising therapeutic approach…

Note: This story was updated Nov. 26, 2025, to correct that the cladribine formulation being tested as a potential gMG treatment differs from the one used in Mavenclad, an approved therapy for multiple sclerosis. The U.S. Food and Drug Administration (FDA) has granted fast track designation to cladribine, an…