News

Immune cell types may predict recovery in MG, study finds

People who recover from myasthenia gravis (MG) after long-term treatment have higher numbers of certain subsets of monocytes — a type of immune cell — and lower numbers of others, a small study in China found. “Consistent with previous studies, our study further validated that dysregulation of immune cells,…

Vyvgart eases gMG, prevents surgery complications: Case study

Vyvgart (efgartigamod) rapidly eased symptoms of generalized myasthenia gravis (gMG) and prevented complications before, during, and after surgery in a 23-year-old woman, a case study reported. The woman required surgery to remove a mass in her abdominal cavity while also experiencing a gMG flare-up. Clinicians successfully removed the…

At-home Rystiggo infusion safe; most MG patients prefer self-care

Rystiggo (rozanolixizumab-noli) can be safely self-administered by people with myasthenia gravis (MG), according to data from a Phase 3 clinical trial. Based on these findings, at-home administration of Rystiggo was authorized earlier in 2025 in Japan and Europe. The work was funded by UCB, the company that sells Rystiggo.

Anxiety due to COVID-19 more prevalent in MG patients vs. public

Anxiety related to COVID-19 is more prevalent among people with myasthenia gravis (MG) than among the general population, a study in Germany shows. For individuals with MG, the most pronounced cause of such anxiety was the fear patients experienced about the consequences of a COVID-19 infection on their health.

Live webinar Oct. 23 on managing MG with support and confidence

A live, virtual panel at 6 p.m. EST on Oct. 23 will explore how people with myasthenia gravis (MG) can make lifestyle changes to reduce flares, have a more supportive relationship with their healthcare team, and find reliable information about the neuromuscular disorder. The free webinar, “Pushing Back…

FDA grants orphan drug designation to CNP-106 for gMG

The U.S. Food and Drug Administration (FDA) has granted orphan drug designation to CNP-106, an experimental treatment that Cour Pharmaceuticals is developing to reprogram the immune system in generalized myasthenia gravis (gMG). “Receiving orphan drug designation for CNP-106 is an important development and regulatory milestone for our…

Blood proteins may predict success of gMG treatments

Measuring changes in blood levels of two proteins — neurofilament light chain (NfL) and calprotectin (CLP) — may show how well people with generalized myasthenia gravis (gMG) respond to Ultomiris (ravulizumab) and Vyvgart (efgartigimod). That’s according to a small, real-world study in Germany that found that rising…

Black patients with generalized MG may face health inequities: Study

Black patients with generalized myasthenia gravis (gMG) face significantly higher risks of exacerbations compared with their white counterparts, according to a retrospective analysis of healthcare insurance claims from a U.S. database. Exacerbations refer to the worsening of existing symptoms or the appearance of new ones. “Interventions aimed at addressing…