A new study shows how Cour Pharmaceuticals‘ nanoparticle platform is able to modulate immune system activity, lending support for the company’s experimental treatments. Cour’s CNP-106, an experimental treatment for generalized myasthenia gravis, is currently being tested in a Phase 1b/2a clinical trial (NCT06106672), which may still be…
News
An elevated triglyceride-glucose (TyG) index, a blood marker of insulin resistance, may be a useful biomarker to identify people at risk of developing myasthenia gravis (MG) associated with a thymoma, or thymus tumor, a study suggested. Insulin resistance refers to the body’s impaired response to insulin, a hormone that…
Telitacicept safely and effectively reduces disease severity in people with generalized myasthenia gravis (MG) associated with anti-AChR antibodies, including when the disease is hard to treat or associated with a thymus tumor, a small study in China showed. “Clinical outcomes showed increased efficacy of telitacicept when used earlier…
About half of people with myasthenia gravis (MG) experience symptoms of urinary incontinence, while about one-third have signs of an overactive bladder, with an urgent need to urinate. That’s according to a recent study in Israel, which also found that patients with late-onset MG had a higher prevalence of…
Some people with well-controlled myasthenia gravis (MG) may be able to stop azathioprine or mycophenolate mofetil after a prolonged period of stable disease, though relapse remains possible, a small single-center real-world study suggests. The study, “Prognosis After Discontinuation of Azathioprine or Mycophenolate Mofetil in Well-Controlled…
Thymectomy, the surgical removal of the thymus, may be an effective therapeutic option for people with late-onset myasthenia gravis (LOMG) without increasing the risk of surgical complications. That’s according to a study in China, which also demonstrated that LOMG patients who underwent the surgical procedure were about 2.4…
New research reveals that race and ethnicity significantly influence how myasthenia gravis (MG) manifests in U.S. patients, with African American and Hispanic individuals developing the autoimmune condition at much younger ages and experiencing more severe initial symptoms. The study, drawing from two large national databases, highlights a stark divide…
The U.S. Food and Drug Administration (FDA) granted priority review to Argenx’s application seeking to expand the approval of Vyvgart (efgartigimod alfa-fcab) to adults with generalized myasthenia gravis (gMG) who test negative for anti-acetylcholine receptor (AChR) antibodies. If the supplemental biologics license application is approved, the infusion…
Dysphagia, or difficulty swallowing, is highly prevalent in people with myasthenia gravis (MG) and may be associated with severe complications, including lung infections caused by food aspiration into the airways. That is according to a review of studies assessing dysphagia in MG patients using objective instrumental tests and subjective…
Women with myasthenia gravis (MG) have a higher risk of pregnancy complications, particularly preeclampsia, and their babies are more likely to be born prematurely and small for their gestational age, according to a study in the U.S. Preeclampsia is a serious pregnancy complication marked by new-onset high blood pressure…
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