News

MGFA Session 2025: Telitacicept eases gMG symptoms long term

Nearly one year of treatment with Remegen’s telitacicept in a clinical trial in China led to substantial and sustained reductions in symptom severity among adults with generalized myasthenia gravis (gMG). That’s according to new results from the Phase 3 trial, which were shared during the Myasthenia Gravis…

MGFA Session 2025: Gefurulimab eases symptoms in gMG trial

Weekly treatment with gefurulimab —an investigational C5 inhibitor from Alexion, Astrazeneca Rare Disease, that’s designed to be self-administered — led to early and sustained reductions in disease severity for adults with generalized myasthenia gravis (gMG), according to top-line data from a Phase 3 clinical trial. The findings…

MGFA Session 2025: Vyvgart eases seronegative gMG disease severity

Vyvgart (efgartigimod alfa-fcab) led to significant and clinically meaningful reductions in disease severity among adults with generalized myasthenia gravis (gMG) who test negative for disease-causing antibodies targeting the acetylcholine receptor (AChR). Notably, benefits were seen across different subgroups of anti-AChR antibody-negative patients, who are also known as having…

Immune cell types may predict recovery in MG, study finds

People who recover from myasthenia gravis (MG) after long-term treatment have higher numbers of certain subsets of monocytes — a type of immune cell — and lower numbers of others, a small study in China found. “Consistent with previous studies, our study further validated that dysregulation of immune cells,…

Vyvgart eases gMG, prevents surgery complications: Case study

Vyvgart (efgartigamod) rapidly eased symptoms of generalized myasthenia gravis (gMG) and prevented complications before, during, and after surgery in a 23-year-old woman, a case study reported. The woman required surgery to remove a mass in her abdominal cavity while also experiencing a gMG flare-up. Clinicians successfully removed the…