Robotic thymectomy — a surgical removal of the thymus gland using robotic systems — is an effective and safe treatment for people with late-onset myasthenia gravis (MG), including those who develop the rare neuromuscular disease after the age of 65, according to a two-decade-long study in China. Rates…
News
A single course of six once-weekly infusions of Descartes-08, an investigational CAR T-cell therapy, was well tolerated and resulted in sustained clinically meaningful responses in people with generalized myasthenia gravis (gMG). That’s according to final data from the Phase 2b MG-001 clinical trial (NCT04146051), which also showed…
People with myasthenia gravis (MG) who take corticosteroids, especially at higher cumulative doses, face an increased risk of developing other health conditions, according to a study in the U.S. Patients are at risk for conditions including diabetes, infections, and cardiovascular diseases, the researchers found. “Our findings highlight the importance…
A new study shows how Cour Pharmaceuticals‘ nanoparticle platform is able to modulate immune system activity, lending support for the company’s experimental treatments. Cour’s CNP-106, an experimental treatment for generalized myasthenia gravis, is currently being tested in a Phase 1b/2a clinical trial (NCT06106672), which may still be…
An elevated triglyceride-glucose (TyG) index, a blood marker of insulin resistance, may be a useful biomarker to identify people at risk of developing myasthenia gravis (MG) associated with a thymoma, or thymus tumor, a study suggested. Insulin resistance refers to the body’s impaired response to insulin, a hormone that…
Telitacicept safely and effectively reduces disease severity in people with generalized myasthenia gravis (MG) associated with anti-AChR antibodies, including when the disease is hard to treat or associated with a thymus tumor, a small study in China showed. “Clinical outcomes showed increased efficacy of telitacicept when used earlier…
About half of people with myasthenia gravis (MG) experience symptoms of urinary incontinence, while about one-third have signs of an overactive bladder, with an urgent need to urinate. That’s according to a recent study in Israel, which also found that patients with late-onset MG had a higher prevalence of…
Some people with well-controlled myasthenia gravis (MG) may be able to stop azathioprine or mycophenolate mofetil after a prolonged period of stable disease, though relapse remains possible, a small single-center real-world study suggests. The study, “Prognosis After Discontinuation of Azathioprine or Mycophenolate Mofetil in Well-Controlled…
Thymectomy, the surgical removal of the thymus, may be an effective therapeutic option for people with late-onset myasthenia gravis (LOMG) without increasing the risk of surgical complications. That’s according to a study in China, which also demonstrated that LOMG patients who underwent the surgical procedure were about 2.4…
New research reveals that race and ethnicity significantly influence how myasthenia gravis (MG) manifests in U.S. patients, with African American and Hispanic individuals developing the autoimmune condition at much younger ages and experiencing more severe initial symptoms. The study, drawing from two large national databases, highlights a stark divide…
Recent Posts
- I do not want to lose myself to myasthenia gravis
- Robotic thymectomy is safe, effective for MG patients even after age 65
- My cousins’ love and loyalty remind me to choose connection, not division
- CAR T-cell therapy offers year-long relief for gMG patients in trial
- Corticosteroid use in MG raises risk of developing other conditions