Blocking the signals of the interleukin-9 receptor, or IL-9R, delayed the progression of myasthenia gravis and reduced symptoms of the disease in rats, a study reports. The study, “Exogenous IL-9 Ameliorates Experimental Autoimmune Myasthenia Gravis Symptoms in Rats,” was published in the journal of…
An interventional program composed of physical activity and psychological support may help improve fatigue levels in myasthenia gravis patients, a small pilot trial found. The results, however, were not sustained over time, and a bigger study is needed, researchers said. The study titled “A Physical and Psychological Approach to…
A small but significant percentage of myasthenia gravis (MG) patients remain resistant to current therapies, which severely impacts on their quality of life and requires greater attention and more aggressive treatments, according to a recent opinion piece from a neurologist. The article, “Refractory Myasthenia Gravis – Patient Burden…
Protalex’s lead treatment candidate PRTX-100 again showed the potential to lessen disease activity and preserve grip strength in a second study in a mouse model of myasthenia gravis (MG). These findings, from an interim analysis of a study led by researchers at George Washington University, are intended to to…
Treatment with Qiangji Jianli (QJJL) decoction, a traditional Chinese medicine, improved energy metabolism and the structure of mitochondria in a rat model of myasthenia gravis (MG), researchers in China report, suggesting it might be a promising therapy for the condition. The study, “Effect of Qiangji Jianli decoction on mitochondrial…
The clinical-stage biotech company argenx is planning to start a pivotal Phase 3 trial of efgartigimod (ARGX-113) for generalized myasthenia gravis (gMG) before the end of the year. The company announced it has received guidance from the U.S. Food and Drug Administration following an End-of-Phase 2 meeting. The Phase…
For the first time, a case of myasthenia gravis in combination with damaged bone marrow and an inflammatory muscle disease was reported in a patient. This rare case was described in the journal Case Reports in Neurology, in the study “Autologous Bone Marrow Transplantation for Polymyositis…
As President Trump signed the recently passed Right to Try legislation into law in a White House ceremony, Jordan McLinn of Indianapolis tried twice to embrace him. The third time, 9-year-old Jordan finally got the hug he wanted — as well as a kiss on the forehead. The video of…
Between 30 percent and 50 percent of all thymoma patients – people treated for a tumor in the thymus gland – go on to develop myasthenia gravis, and as a case study reports, this disease’s appearance can sometimes be associated with a return of the cancer. The study detailed an…
Finding treatments and potential cures for rare diseases is crucial, but so is the quality of patients’ lives — a rather nebulous term that means different things to different people. “Recently, there’s been much more of a focus on Quality of Life (QoL) issues, real-world evidence and patient-reported outcomes,” said…
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