Protalex’s lead treatment candidate PRTX-100 again showed the potential to lessen disease activity and preserve grip strength in a second study in a mouse model of myasthenia gravis (MG). These findings, from an interim analysis of a study led by researchers at George Washington University, are intended to to…
Treatment with Qiangji Jianli (QJJL) decoction, a traditional Chinese medicine, improved energy metabolism and the structure of mitochondria in a rat model of myasthenia gravis (MG), researchers in China report, suggesting it might be a promising therapy for the condition. The study, “Effect of Qiangji Jianli decoction on mitochondrial…
The clinical-stage biotech company argenx is planning to start a pivotal Phase 3 trial of efgartigimod (ARGX-113) for generalized myasthenia gravis (gMG) before the end of the year. The company announced it has received guidance from the U.S. Food and Drug Administration following an End-of-Phase 2 meeting. The Phase…
For the first time, a case of myasthenia gravis in combination with damaged bone marrow and an inflammatory muscle disease was reported in a patient. This rare case was described in the journal Case Reports in Neurology, in the study “Autologous Bone Marrow Transplantation for Polymyositis…
As President Trump signed the recently passed Right to Try legislation into law in a White House ceremony, Jordan McLinn of Indianapolis tried twice to embrace him. The third time, 9-year-old Jordan finally got the hug he wanted — as well as a kiss on the forehead. The video of…
Between 30 percent and 50 percent of all thymoma patients – people treated for a tumor in the thymus gland – go on to develop myasthenia gravis, and as a case study reports, this disease’s appearance can sometimes be associated with a return of the cancer. The study detailed an…
Finding treatments and potential cures for rare diseases is crucial, but so is the quality of patients’ lives — a rather nebulous term that means different things to different people. “Recently, there’s been much more of a focus on Quality of Life (QoL) issues, real-world evidence and patient-reported outcomes,” said…
Treatment with Rituxan (rituximab) provided sustained clinical improvement, increased muscle strength, and extended the time before disease worsening in myasthenia gravis, according to researchers. It also allows myasthenia gravis (MG) patients who are resistant to conventional treatment to reduce their dose…
Concentric needle-jitter is more accurate in diagnosing myasthenia gravis (MG) than repetitive nerve stimulation or acetylcholine receptor antibody positivity, a study reports. The study, “Repetitive nerve stimulation and jitter measurement with disposable concentric needle electrode in newly diagnosed myasthenia gravis patients,” was published in the journal…
Careful patient assessment and planning prior to surgery was needed to successfully remove a tumor from the thymus of a myasthenia gravis patient with a recent history of adult respiratory distress syndrome, researchers in Greece reported. Their case study, “Thymectomy in a patient with thymoma -related myasthenia Gravis and recent…
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