News

Tacrolimus is effective and safe as a single-agent immunotherapy for people with myasthenia gravis (MG), and its use led to minimal manifestation status in a majority of patients treated for one year in China, a study reported. Favorable responses were particularly evident in younger patients (up to age 40),…

Scientists described a new cellular model of the neuromuscular junction that could be useful for diagnosing myasthenia gravis (MG) or developing new treatments for the condition. “New approaches for the treatment of neurodegenerative diseases are sorely needed, as decades of research have resulted in limited therapeutic advances. We hope…

By analyzing available research and conducting nearly 100 interviews with patients, an international team of researchers crafted a new tool to measure the severity of myasthenia gravis (MG) based on patient experiences. Called MG Symptoms PRO, this tool has the potential to aid clinical trials by better capturing a…

Argenx is working toward the commercial launch of Vyvgart (efgartigimod) — recently approved by the U.S. Food and Drug Administration (FDA) — to treat adults in the U.S. with generalized myasthenia gravis (gMG) who have the most common type of MG-driving antibody. Vyvgart currently is up for…

Immunovant is moving forward with its Phase 3 clinical trial in the U.S. to evaluate the investigational myasthenia gravis (MG) therapy batoclimab in the first half of this year. The announcement came after the company reached an agreement with the division of neurology within the U.S. Food…

Throughout 2021, Myasthenia Gravis News has brought you coverage on the latest scientific advancements and clinical trials related to myasthenia gravis (MG). We look forward to continuing to be a resource to the MG community across 2022. Here are the top 10 most-read MG news stories of 2021, along with a…

Infants born to women with myasthenia gravis (MG) may develop a rare condition called transient neonatal myasthenia gravis (TNMG), which needs to be properly recognized in order to be appropriately managed, a new report highlights. “A neonate [newborn] born to a mother with MG is at risk for…

Merck KGaA has acquired Chord Therapeutics and the rights to continue developing CRD1 (cladribine), Chord’s lead candidate for treatment of generalized myasthenia gravis. “I am particularly pleased that Chord’s focus on severe, rare neurological conditions will be complemented by Merck’s established leadership with cladribine,” Arthur Roach, founder and…

The U.S. Food and Drug Administration (FDA) has accepted and placed on priority review an application seeking the approval of Ultomiris (ravulizumab-cwvz) to treat adults with generalized myasthenia gravis (gMG). The FDA set April through June as a target date range for its decision. Ultomiris is a monoclonal antibody…

Treatment with Ultomiris (ravulizumab-cwvz), a complement-blocking therapy, quickly eased symptom severity in adults with generalized myasthenia gravis (gMG), according to data from a Phase 3 trial. Findings were shared at the Myasthenia Gravis Foundation of America (MGFA) Scientific Sessions 2021 in the presentation, “Efficacy and safety…