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January 15, 2019January 15, 2019

MG-ADL Symptom Scale Would Benefit from Questions on Generalized Weakness, Study Says

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MG-ADL, a patient-reported scale commonly used to address symptom severity in myasthenia gravis (MG), has a poor sensitivity for measuring generalized muscle weakness. Researchers suggest that more questions about ... Read more

January 10, 2019January 10, 2019

Phase 2b Trial Finds Firdapse Effective, Safe in Adults with MuSK-MG

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Treatment of adult MuSK-antibody positive myasthenia gravis (MuSK-MG) patients with the investigational therapy Firdapse (amifampridine phosphate) improved muscle strength, eased fatigue, and was safe, according to full results of a Phase 2b ... Read more

January 8, 2019January 8, 2019

Researchers Develop New Test for Rapid, Less-costly Test to Detect Anti-AChR Antibodies in Myasthenia Gravis Patients

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A new test offers a rapid, sensitive and inexpensive way to detect anti-acetylcholine receptor (AChR) antibodies in patients with myasthenia gravis (MG). The study with that finding, “A Simple, ... Read more

January 3, 2019January 3, 2019

Common Clinical Scales Insufficient to Evaluate Swallowing Problems in MG Patients, Study Reports

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Commonly used clinical scales to measure symptom severity in myasthenia gravis (MG) patients are insufficient to precisely evaluate swallowing problems and predict the risk of silent aspiration, a study ... Read more

December 20, 2018December 20, 2018

Rising Healthcare Costs Strain EU Budgets Even as New Therapies Flourish

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Cash-strapped governments across the 28-member European Union are struggling to control runaway healthcare expenditures — at exactly the same time as the promise of new but expensive therapies to ... Read more

December 18, 2018December 18, 2018

Ice Pack Test Diagnoses Patient Undergoing Myasthenic Crisis, Case Study Reports

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A patient with symptoms of a myasthenic crisis was successfully diagnosed with myasthenia gravis (MG), using an approach called the ice pack test, a case study reports. The study, ... Read more

December 13, 2018December 13, 2018

Ra Pharma’s Zilucoplan Shows Promise as Self-administered Myasthenia Gravis Therapy

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Topline results from a Phase 2 trial of Ra Pharma’s zilucoplan (previously known as RA101495), a potential self-administered therapy for patients with generalized myasthenia gravis (MG), showed a statistically significant decrease ... Read more

December 7, 2018December 11, 2018

Myasthenia Gravis Patients’ Gut Microbiome Less Diverse, More Pro-Inflammatory, Study Shows

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The gut microbiome of people with myasthenia gravis is less diverse than that of healthy people, with a rise in pro-inflammatory bacteria and a reduction in protective molecules, a ... Read more

December 4, 2018December 4, 2018

Prograf Has Potential to Ease Inflammatory Immune Response in MuSK MG Patients, Study Finds

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Prograf (tacrolimus) suppressed the proliferation and inflammatory responses of specific immune cells collected from patients with MuSK-antibody positive myasthenia gravis (MuSK-MG), a new study. These results provide early evidence ... Read more

November 27, 2018November 27, 2018

Gender Differences in MG Onset Shift After Age 40, Study Reports

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Myasthenia gravis (MG) onset is more common in men ages 40-70 than in women in the same age range. There are also gender differences in the incidence of MG-related ... Read more

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