Measuring changes in blood levels of two proteins — neurofilament light chain (NfL) and calprotectin (CLP) — may show how well people with generalized myasthenia gravis (gMG) respond to Ultomiris (ravulizumab) and Vyvgart (efgartigimod). That’s according to a small, real-world study in Germany that found that rising…
Black patients with generalized myasthenia gravis (gMG) face significantly higher risks of exacerbations compared with their white counterparts, according to a retrospective analysis of healthcare insurance claims from a U.S. database. Exacerbations refer to the worsening of existing symptoms or the appearance of new ones. “Interventions aimed at addressing…
Rituximab may be safe and effective in treating women with myasthenia gravis (MG) that’s driven by antibodies that target muscle-specific tyrosine kinase (MuSK), an analysis of patients at a single center in China shows. Significant symptom relief was seen by 90% of patients after a month of treatment and it…
People with myasthenia gravis (MG) face a mean annual healthcare cost of nearly $16,000, according to a survey of MG patients and their caregivers. Medications and treatments accounted for most out-of-pocket expenses (27%), followed by insurance premiums (20%), diagnosis (15%), and caregiving assistance (14%). “Disseminating the findings of this…
A man with a 16-year history of hard-to-treat generalized myasthenia gravis finally saw his disease successfully managed with Soliris (eculizumab) and then with Ultomiris (ravulizumab) — highlighting the efficacy of these newer treatments for myasthenia gravis (MG) — according to a new case study. Indeed, its author called…
The China National Food and Drug Administration has accepted and placed under priority review an application from Remegen seeking approval of telitacicept as a treatment for generalized myasthenia gravis (gMG). That’s according to a press release from Remegen, a commercial-stage biotechnology company that’s developing the treatment…
Among people with myasthenia gravis (MG), the degree of daily activity impairment is greater for those with more severe and more widespread muscle weakness, according to real-world data from a survey of physicians in the U.S. and Europe. However, the study — which involved clinicians treating more than…
Intravenous (into-the-vein) treatment with Argenx’s Vyvgart (efgartigimod alfa) resolved a myasthenic crisis — a life-threatening complication of myasthenia gravis (MG) marked by severe breathing problems — in a 57-year-old man who had failed to respond to prior treatments, according to a case study. The findings…
Adolescent girls with juvenile myasthenia gravis (JMG) were more likely to have enlarged thymus glands than younger girls and adults with myasthenia gravis (MG), according to a retrospective study in France. The higher levels of female hormones during puberty may explain these results, the researchers noted, supporting the potential…
The incidence and prevalence of myasthenia gravis (MG) among the population in France are higher than reported for other European countries. That’s according to a retrospective population-based study, which also found the incidence of MG tended to increase with age and was associated with a higher risk of cancer.
Get regular updates to your inbox.
