Marisa Wexler, MS, senior science writer —

Cartesian Therapeutics is planning to launch a pivotal, Phase 3 clinical trial of its experimental cell therapy Descartes-08 in people with myasthenia gravis (MG), following positive data from an ongoing Phase 2 study in patients. The company announced that it recently completed a meeting with the…

A machine learning model taking into account markers of inflammation and clinical data may accurately predict whether people with generalized myasthenia gravis (gMG) are likely to see their disease symptoms ease after six months of standard treatment. Researchers described the new tool in the study, “Interpretable…

Treatment with Soliris (eculizumab) was effective for managing myasthenic crisis in four people with myasthenia gravis (MG) at a center in China, a study reported. “[Soliris] exhibited a tolerable and efficacious profile in treating patients with [myasthenic crisis],” the researchers wrote, adding that “larger sample sizes and longer…

People with generalized myasthenia gravis (gMG) with many hospital visits before diagnosis or hard-to-manage disease symptoms at the time of diagnosis tend to accrue higher healthcare-related costs after getting diagnosed, a new study reports. The use of certain treatments before diagnosis and in the year after, as well…

The case of a pregnant woman with myasthenia gravis (MG) who saw her disease worsen and who developed hydramnios — an abnormal buildup of fluid around the fetus during pregnancy — was described in a new report that researchers say highlights how variable the condition can be. Despite the…

A traditional Chinese medicine practice that combines acupuncture and moxibustion, given along with standard treatments, may ease symptoms for people with myasthenia gravis (MG) more effectively than conventional medications alone. That’s according to “Acupuncture and moxibustion treatment for myasthenia gravis: A systematic review and meta-analysis,” which…

Vyvgart (efgartigimod) eased symptoms of generalized myasthenia gravis (gMG) for some patients in Japan and the therapy’s effects didn’t appear to be influenced by the type of MG-driving antibody each patient had, a new analysis shows. The study, “Therapeutic Responses to Efgartigimod for Generalized Myasthenia…

Treatment with an oral version of salbutamol, the active ingredient of medications used for asthma and other respiratory conditions, may help ease symptoms in some people with MuSK-positive myasthenia gravis (MG), a small study reports. The study was published as a letter to the editor, titled “…

Dianthus Therapeutics is launching a Phase 2 clinical trial to test its experimental therapy, DNTH103, in people with generalized myasthenia gravis (gMG). Called MaGic, the trial is expected to enroll up to 60 people with gMG who are positive for antibodies that target the acetylcholine receptor (AChR), the…

An under-the-skin or subcutaneous injection formulation of efgartigimod has been approved in Japan for use by adults with generalized myasthenia gravis (gMG) who do not sufficiently respond to first-line treatment with steroids or non-steroidal immunosuppressive therapies. In Japan, the now-approved therapy — efgartigimod alfa and hyaluronidase-qvfc — will be…