Andrea Lobo

Andrea Lobo is a Science writer at Bionews since 2022. She holds a PhD in Cell Biology/Neurosciences, where she studied the molecular pathways that contribute to neurodegeneration/neuroprotection in stroke biology. Between 2011 and 2021, she worked as a postdoctoral and senior researcher at the Institute for Research and Innovation in Health in Porto, focused on the molecular mechanisms involved in drug addiction, particularly neuronal plasticity and remodeling induced by amphetamines. As a research scientist for 19 years, Andrea also participated in academic projects in other research fields, including gene regulation, cancer, and rare diseases. During her professional journey, Andrea also developed her science writing skills by writing/editing scientific papers and grant proposals.

Education

• PhD, Cell Biology/Neuroscience, University of Coimbra, Portugal, 2011
• BSc Biology, University of Coimbra, Portugal, 2002

Professional Organizations and Affiliations

• Member of the Portuguese Society of Medical Writers

Published Works

• Amado, B.; Melo, L.; Pinto, R.; Lobo, A.; Barros, P.; Gomes, J. R. “Ischemic Stroke, Lessons from the Past towards Effective Preclinical Models”. Biomedicines, 2022. DOI: 10.3390/biomedicines10102561.
• Pinto, R.; Matula, J.; Gomez-Lazaro, M.; Sousa, M.; Lobo, A.; Zikmund, T.; Kaiser, J.; Gomes, J.R. “High-resolution micro-CT for 3D infarct characterization and segmentation in mice stroke models.” Scientific Reports 2022. DOI: 10.1038/s41598-022-21494-9.
• Pinto, R.; Magalhães, A., Sousa, M.; Melo, L.; Lobo, A.; Barros, P.; Gomes, J.R. "Bridging the transient intraluminal stroke preclinical model to clinical practice: from improved surgical procedures to a workflow of functional tests." Frontiers Neurology 2022. DOI: 10.3389/fneur.2022.846735.
• Bravo, J.; Ribeiro, I.; Terceiro, A. F.; Andrade, E.B.; Portugal, C. C.; Lopes, I. M.; Azevedo, M. M.; Sousa, M.; Lopes, C.; Lobo, A.; Canedo, T.; Relvas, J. B.; Sumavielle, T. "Neuron–Microglia Contact-Dependent Mechanisms Attenuate Methamphetamine-Induced Microglia Reactivity and Enhance Neuronal Plasticity"." Cells 11 3 (2022): 355. DOI: 10.3390/cells11030355.
• Gomes, João R*; Lobo, Andrea*; Nogueira, Renata; Terceiro, Ana F; Costelha, Susete; Lopes, Igor M; Magalhães, Ana; Summavielle, Teresa; Saraiva, Maria J. "Neuronal megalin mediates synaptic plasticity—a novel mechanism underlying intellectual disabilities in megalin gene pathologies"." Brain Communications 2020, DOI: 10.1093/braincomms/fcaa135. (* co-first authors).
• Sousa, N. A.; Oliveira, G.; de Oliveira, A.; Lopes, A.; Iles, B.; Nogueira, K..; Araújo, T.; Souza, L.; Araújo, A.; Ramos-Jesus, J., Plácido, A.; Amaral, C.; Campelo, Y.; Barbosa, E.; Portugal, C.; Socodato, R.; Lobo, A.; et al. "Novel Ocellatin Peptides Mitigate LPS-induced ROS Formation and NF-kB Activation in Microglia and Hippocampal Neurons." Scientific Reports (2020). DOI: 10.1038/s41598-020-59665-1.
• Braz, Sandra Oliveira*; Cruz, Andrea*; Lobo, Andrea* (co-first authors); Bravo, Joana; Moreira-Ribeiro, Joana; Pereira-Castro, Isabel; Freitas, Jaime; et al. "Expression of Rac1 alternative 3' UTRs is a cell-specific mechanism with a function in dendrite outgrowth in cortical neurons." Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms (2017). DOI: 10.1016/j.bbagrm.2017.03.002. (* co-first authors).
• Baptista, Sofia; Bento, Ana Rita; Gonçalves, Joana; Bernardino, Liliana; Summavielle, Teresa; Lobo, Andrea; Fontes-Ribeiro, Carlos; et al. "Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures." Neuropharmacology (2012). DOI: 10.1016/j.neuropharm.2012.02.015.
• Lobo, Andrea C.; Gomes, João R.; Catarino, Tatiana; Mele, Miranda; Fernandez, Pedro; Inácio, Ana R.; Bahr, Ben A.; et al. "Cleavage of the vesicular glutamate transporters under excitotoxic conditions." Neurobiology of Disease (2011). DOI: 10.1016/j.nbd.2011.07.010.
• Gomes, J. R.; Lobo, A. C.; Melo, C. V.; Inacio, A. R.; Takano, J.; Iwata, N.; Saido, T. C.; et al. "Cleavage of the Vesicular GABA Transporter under Excitotoxic Conditions Is Followed by Accumulation of the Truncated Transporter in Nonsynaptic." Journal of Neuroscience (2011). DOI: 10.1523/jneurosci.3541-10.2011.

Professional Accomplishments

• Award of Best Paper 2012 in Molecular and Cellular Neurobiology, for a paper published as second author in the Journal of Neuroscience

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