Jacob Harney, PhD

Jake joined Bionews in 2021 after 26 years in higher education teaching, conducting biomedical research and serving in administration. He presently serves as the news reporter and a periodic science writer.

Education

• PhD, Reproductive Physiology, University of Florida, 1992
• MS, Reproductive Physiology, University of Florida, 1988
• BS, Animal Science, University of Connecticut, 1985

Professional Organizations and Affiliations

• Sigma Xi, The Scientific Research Honor Society
• Reinhardt University, 2015-2021

Published Works

• Harney, J.P., Gudsnuk, K., Patel, A., Vellipuram, A.R., Bandaru, S., & Butler, D. (2017). Endocrine and Reproductive Effects of Ketogenic Diets. In S.A. Masino (Ed.), Ketogenic Diet and Metabolic Therapies (pp. 227-240). New York, NY: Oxford University Press.
• Scichilone, J., K. Yarraguntla, D. Butler, Charalambides, A., Harney J.P., & D.A. Butler, 2016. Environmental Enrichment Mitigates Effects of Ketogenic Diet in Weanling Rats. J Mol. Neurosci. 60:1-9
• Bandaru, S.S., K. Lin, S.L. Roming, R. Vellipuram & J.P. Harney, 2010. Effects of PI3K Inhibition and Low Docosahexaenoic Acid on Cognition and Behavior. Physiology and Behavior 100:239-244.
• Walf, A.A., M.E. Rhodes, J.R. Meade, J.P. Harney & C.A. Frye, 2007. Estradiol-induced conditioned place preference may require actions at estrogen receptors in the nucleus accumbens. Neuropsychopharmacology 32:522-30.
• Frye, C.A., K. Sumida, B.C. Dudek, J.P. Harney, J.P. Lydon, B.W, O’Malley, D.W. Pfaff & M.E. Rhodes. 2006. Progesterone’s effects to reduce anxiety behavior or aged mice do not require actions via intracellular progestin receptors. Psychopharmacology 186:312-22.
• Frye, C.A., M.E. Rhodes, J. Talluri & J.P. Harney, 2005. Ketogenic diet decreases circulating concentrations of neuroactive steroids in female rats. Epilepsy Behav 7:231-9.
• Frye, C.A., A.A. Walf, M.E. Rhodes & J.P. Harney, 2004. Progesterone enhances motor, anxiolytic, analgesic, and anti-depressive behavior of wild type mice, but not those deficient in 5-reductase. Brain Research 1004(1-2):116-124.
• Rhodes, M.E., J.P. Harney & C.A. Frye. 2004. Gonadal, adrenal, and neuroactive steroids' role in ictal activity. Brain Research 1000(1-2):8-18.
• Frye, C.A., M.E. Rhodes, A. Walf & J.P. Harney. 2002. Progesterone reduces pentylenetetrazol-induced ictal activity of wild type mice but not those deficient in type I 5-reductase. Epilepsia 43(s5):14-17.
• Frye, C.A., M.E. Rhodes, A. Walf & J.P. Harney. 2002. Testosterone enhances aggression of wild type mice but not those deficient in type I 5-reductase. Brain Research 948(1-2): 165-170.
• Harney, J.P., J. Madara, J. D. Madara & H. I’Anson. 2002. Effects of acute inhibition of fatty acid oxidation on latency to seizure and concentrations of hydroxybutyrate in plasma of rats maintained on calorie restriction and/or the ketogenic diet. Epilepsy Res. 49:239-246.
• Frye, C.A., M.E. Rhodes, A. Walf & J.P. Harney. 2001. Testosterone reduces pentylenetetrazol-induced ictal activity of wild type mice but not those deficient in type I 5-reductase. Brain Research 918:182-186.
• Hinkle, D.A., J.P. Harney, A. Cai, D.C. Hilt, P.J. Yarowsky & P.M. Wise. 1997. Basic fibroblast growth factor-2 and interleukin-1 regulate S100 expression in cultured astrocytes. Neuroscience 82:33-41
• Wise, P.M., M.L. Kashon, K.M. Krajnak, K.L. Rosewell, A. Cai, K. Scarbrough, J.P. Harney, T. McShane, J.M. Lloyd & N.G. Weiland. 1997. Aging of the female reproductive system: a window into brain aging. Recent Progress Hormone Research 52:279-305.
• Harney, J.P., K. Scarbrough, K.L. Rosewell & P.M. Wise. 1996. In vivo antisense antagonism of vasoactive intestinal polypeptide in the suprachiasmatic nuclei causes aging-like changes in the estradiol-induced luteinizing hormone and prolactin surges. Endocrinology 137:3696-3701.
• Scarbrough, K., J.P. Harney, K.L. Rosewell & P.M. Wise. 1996. Acute effects of antisense antagonism of a single peptide neurotransmitter in the circadian clock. Amer. Jour. Physiol. 270:R283-R288.
• Tuo, W., J.P. Harney & F.W. Bazer. 1996. Developmentally regulated expression of interleukin-1ß by peri-implantation conceptuses of swine. J. Reprod. Immunol. 31:185-198.
• Buhi, W.C., I.M. Alvarez, V.M. Shille, M.J. Thatcher, J.P. Harney & M. Cotton. 1995. Purification and characterization of a uterine retinol-binding protein in the bitch. Biochem. J. 311:407-415.
• Tuo, W., J.P. Harney & F.W. Bazer. 1995. Colony stimulating factor-1 in conceptus and uterine tissues in pigs. Biol. Reprod. 53:133-142.
• Harney, J.P., M. Ali, W.V. Vedeckis & F.W. Bazer. 1994. Porcine conceptus and endometrial retinoid-binding proteins. Reprod. Fertil. Develop. 6:211-219.
• Harney, J.P., L.C. Smith, R.C.M. Simmen, A.E. Fliss & F.W. Bazer. 1994. Retinol-binding protein: Immunolocalization of protein and abundance of messenger ribonucleic acid in conceptus and maternal tissues during pregnancy in pigs. Biol. Reprod. 50:1126-1135.
• Wise, P.M., K. Scarbrough, J. Lloyd, A. Cai, J. Harney, S. Chiu, D. Hinkle & T. McShane. 1994. Neuroendocrine concomitants of reproductive aging. Exper. Gerontol. 29:275-283.
• Geisert, R.D., R.M. Brenner, R.J. Moffatt, J.P. Harney, T. Yellin & F.W. Bazer. 1993. Changes in oestrogen receptor protein, mRNA expression and localization in the endometrium of cyclic and pregnant gilts. Reprod. Fertil. Develop. 5:247-260.
• Harney, J.P., T.L. Ott, R.D. Geisert & F.W. Bazer. 1993. Retinol-binding protein gene expression in cyclic and pregnant endometrium of pigs, sheep and cattle. Biol. Reprod. 49:1066-1073.
• Mirando, M.A., J.P. Harney, Y. Zhou, T.F. Ogle, T.L. Ott R.J. Moffatt & F.W. Bazer. 1993. Changes in progesterone and oestrogen receptor mRNA and protein, and oxytocin receptors in the endometrium of ewes after intrauterine injection of ovine trophoblast interferon. J. Mol. Endocrinol. 10:185-192.
• Ott, T.L., Y. Zhou, M.A. Mirando, C. Stevens, J.P. Harney, T. Ogle & F.W. Bazer. 1993.Changes in progesterone and oestrogen receptor mRNA and protein during maternal recognition of pregnancy and luteolysis in ewes. J. Mol. Endocrinol. 10:171-183.
• Bazer, F.W., M.A. Mirando, T.L. Ott, J.P. Harney, D.H. Dubois, T.K. Schalue, C. Pontzer, C. Hostetler, H.M. Johnson & T. Ogle. 1992. Roles of ovine trophoblast protein-1 and estradiol/prolactin in establishment of pregnancy in sheep and pigs. Reprod. Fertil. Develop. 4:335-340.
• Beers, S., M.A. Mirando, C.H. Pontzer, J.P. Harney, B.A. Torres, H.M. Johnson & F.W. Bazer. 1990. Influence of the endometrium, protease inhibitors and freezing on antiviral activity of proteins secreted by pig conceptuses. J. Reprod. Fertil. 88:205-211.
• Harney, J.P. & F.W. Bazer. 1990. Effects of conceptus and conceptus secretory products uterine development in the pig. Reprod. Fertil. Dev. 2:179-87.
• Harney, J.P., M.A. Mirando, L.C. Smith & F.W. Bazer. 1990. Retinol-binding protein: a major secretory product of the pig conceptus. Biol. Reprod. 42:523-532.
• Mirando, M.A., J.P. Harney, S. Beers, C.H. Pontzer, B.A. Torres, H.M. Johnson & F.W. Bazer. 1990. Onset of secretion of proteins with antiviral activity by pig conceptuses. J. Reprod. Fertil. 88:197-203.
• Mirando, M.A., M.P.J.M. Leen, S. Beers, J.P. Harney & F.W. Bazer. 1990. Endometrial inositol phosphate turnover in pigs is reduced during pregnancy and estradiol-induced pseudopregnancy. J. Anim. Sci. 68:4285-4291.
• Mirando, M.A., T.L. Ott, J.P. Harney & F.W. Bazer. 1990. Ovine trophoblast protein-1 inhibits development of endometrial responsiveness to oxytocin in ewes. Biol. Reprod. 43:1070-1078.
• Bazer, F.W., J.L. Vallet, J.P. Harney, T.S. Gross & W.W Thatcher. 1989. Comparative aspects of maternal recognition of pregnancy between sheep and pigs. J. Reprod. Fertil. 37 (Suppl. 1):85-89.
• Harney, J.P. & F.W. Bazer. 1989. Effect of porcine conceptus secretory proteins on interestrous interval and uterine secretion of prostaglandins. Biol. Reprod. 41:277-284.
• Gross, T.S., M.C. Lacroix, F.W. Bazer, W.W. Thatcher & J.P. Harney. 1988. Prostaglandin secretion by perfused porcine endometrium: further evidence for an endocrine versus exocrine secretion of prostaglandins. Biol. Reprod. 35:327-341.

Professional Accomplishments

• Full Professor, 2015
• Administrative positions held: Department Chair, School Dean, Associate Provost of Academics, Interim-Provost (1999-2021)
• Two teaching awards, one graduate mentorship award (University of Hartford), two student government association leadership awards (Reinhardt University)
• Principal Investigator of two National Science Foundation teacher/scholar mentorship grants (Reinhardt University)

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