By March, Immunovant plans to initiate four or five pivotal clinical trials of its lead therapeutic candidate IMVT-1402…
Lindsey Shapiro, PhD
Senior Science Writer
Lindsey is a senior science writer for Bionews with a PhD in neuroscience from Emory University. There, she was awarded a predoctoral fellowship from the American Epilepsy Society to study the role of new therapeutic approaches for treatment of resistant forms of epilepsy. She also spent time as a postdoctoral researcher exploring the role of inflammation in epilepsy. With a passion for ensuring that science is accessible to all, Lindsey joined Bionews as a science writer in 2022.
Education
- PhD in neuroscience, Emory University, 2021
- B.S. in neuroscience, The University of New Hampshire, 2014
Published Works
- Cannabidiol Increases Seizure Resistance and Improves Behavior in an Scn8a Mouse Model. Frontiers in Pharmacology, 2022
- Allosteric modulation of the cannabinoid 2 receptor confers seizure resistance in mice. Neuropharmacology, 2021
- Nanoparticle encapsulated oxytocin increases resistance to induced seizures and restores social behavior in Scn1a-derived epilepsy. Neurobiology of disease, 2021
- Pathogenic in-Frame Variants in SCN8A: Expanding the Genetic Landscape of SCN8A-Associated Disease Frontiers in Pharmacology, 2021
- Reduced cannabinoid 2 receptor activity increases susceptibility to induced seizures in mice. Epilepsia, 2019
Professional Accomplishments
- Awarded a predoctoral fellowship from The American Epilepsy Society in 2019
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Articles by Lindsey Shapiro, PhD
Treatment with the investigational CAR T-cell therapy Descartes-08 led to deep and sustained reductions in disease severity among generalized…
Immunovant plans to prioritize development of its newer treatment candidate, IMVT-1402, over its Phase 3 candidate, batoclimab, for…
Cartesian Therapeutics’ investigational cell therapy Descartes-08 has been granted regenerative medicine advanced therapy (RMAT) designation by the U.S. Food…
No significant differences in clinical outcomes or quality of life were observed between myasthenia gravis (MG) patients treated with…
Regulators in the U.K. have approved UCB’s Rystiggo (rozanolixizumab) as an add-on treatment for adults with generalized myasthenia…
Clinical responses to the approved generalized myasthenia gravis (gMG) therapy Zilbrysq (zilucoplan) have now been sustained for more than…
Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) consistently reduced disease severity and improved quality of life across treatment cycles among…
Curcumin therapy — treatment with the traditional Asian medicine, which is the main ingredient in the spice turmeric — was…
Both high-dose intravenous methylprednisolone (IVMP) and tacrolimus effectively reduced symptom severity in patients with ocular myasthenia gravis (OMG) who…