David
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Yes I have had muscle twitching and I can only assume it is from the Mestinon. After awhile, my dosage was reduced but I still have occasional twitching. I have never has a crisis thank the Good Lord and nothing I have found gives me relief from either the twitching or cramping.
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When I was younger was exposed to Chlordane (which was removed from the market because of its danger). My exposure was enough to cause hospitalization for a week. Later on in life was diagnosed with MG. Wonder if there is a correlation?